KRISTY YOUNG JOHNSON, Ph.D.

Date of Birth: March 24, 1970

Home Address: 298 Stefan Dr.

Home Phone: 843-762-3821 Charleston, SC 29412

Office Address: Duckett Hall 316, Biology Dept. The Citadel 171 Moultrie St. Charleston, S.C. 29409

Phone: 843-953-7879

E-mail: johnsonk1@citadel.edu

EMPLOYMENT HISTORY

August 2002 - present: Assistant Professor at The Citadel
- General Biology (lecture and laboratory)
Microbiology (lecture and laboratory)
Genetics (laboratory)
Descriptive Histology (lecture and laboratory)
August 2001 - May 2002: Visiting Assistant Professor at The Citadel
- General Biology (lecture and laboratory)
Microbiology (lecture and laboratory)
June 1998 - June 2001: Post-doctoral fellow at the Medical University of South Carolina
- research topics:
signal transduction pathways involving ras mode of Pseudomonas
aeruginosa
exoenzyme S transmission
- supervisor: Timothy S. Vincent, Ph.D.
January 2001 - May 2001: Adjunct faculty at the Citadel
- Genetics (laboratory)
- supervisor: Col. Robert E. Baldwin, Ph.D.
August 2000 -December 2000: Adjunct faculty at the College of Charleston
- General Chemistry (laboratory)
- supervisor: James Deavor, Ph.D.
January 2000 - May 2000: Adjunct faculty at the Citadel
- Descriptive Histology (lecture and laboratory)
- supervisor: Col. Robert E. Baldwin, Ph.D.

EDUCATION

1992 - 1998: Medical University of South Carolina, Charleston, S. C.
Ph.D., department of Pathology and Laboratory Medicine, May, 1998
Research Topics: Characterization of the phosphorylation of the Bcl-2 oncoprotein
Characterization of a protein antigen lost in apoptotic cell death
Development of a novel nick translation protocol
Screening of various human tissues for reactivity to the B3 antibody
Awards: 1998 Annual Meeting of the American Association for Cancer Research
- selected to participate in Poster Discussion Session
1997 MUSC Student Research Day,
- 2nd place in "Ph.D. 3rd year +" category
Dissertation: Characterization and Analysis of the Hyperphosphorylation of the Bcl-2 Protein.
Advisor: Mark C. Willingham, M.D.
1988 - 1992: Gardner-Webb University, Boiling Springs, N. C.
B.S. in Chemistry with minors in Biology and Religious Education
Honors and Awards: Presidential Scholarship
Dean's List
Alpha Chi
Beta Beta Beta
Honors Program
Graduated magna cum laude
Positions held: Biology Department Assistant/Tutor (1989 - 1992)
- prepared laboratory experiments for General Biology and Microbiology labs
- supervised and assisted students during lab sessions
- provided tutoring services for all students enrolled in General Biology
  Mathematics Department Tutor (1988 - 1989)
- provided tutoring services for all students enrolled in College Algebra
- supervised groups of 15 - 30 students daily

SEMINAR PRESENTATIONS

"Pseudomonas aeruginosa: A Common Yet Dangerous Species"
"Characterization and Analysis of the Hyperphosphorylation of the Bcl-2 Protein"
"Examining the Phosphorylation of the Bcl-2 Protein"
"Characterization and Analysis of the Functional Role of Phosphorylation of the Bcl-2 Protein"
"Phosphorylation: An Overview" "Breast Cancer and BRCA1"
"Do Some Unique Histones Have a Role in Apoptosis?"
"Transfecting Genes Into Mammalian Cells"

PUBLICATIONS

Korey R. Johnson, Kristy Y. Johnson, Kevin P. Becker, Jacek Bielawski, Cungui Mao, and Lina M. Obeid. Role of Human Sphingosine-1-phosphate Phosphatase 1 in the Regulation of Intra- and Extracellular Sphingosine-1-phosphate Levels and Cell Viability. The Journal of Biological. Chemistry, Sep 2003; 278: 34541 - 34547.

Young, K.K. and Vincent, T.S. A Minimal FLAG Sequence Useful in the Functional Epitope Tagging of H-Ras. Biotechniques 32: 1270-1280.

Johnson, K.R., Young, K.K., and Fan, W.F. Antagonistic Interplay Between Antimitotic and G1/S Arresting Agents Observed in Experimental Combination Therapy. Clinical Cancer Research, 5: 2559-2565, 1999.

Collins, J.A., Schandl, C.A., Young, K.K., Vesely, J., and Willingham, M.C. Major DNA Fragmentation is a Late Event in Apoptosis. The Journal of Histochemistry and Cytochemistry, 45 (7): 923-934, 1997.

ABSTRACTS

1. Hollings Cancer Center 1st Annual Research Retreat. August 31, 2001. Mechanisms of Growth Suppression of Cancer Cells by the Monoterperne Perillyl Alcohol. Vincent, T.S., Johnson, K.Y., Re, G., Baker, V., Meier, K.E., and Meier, G.P.

2. Eighty-Ninth Annual Meeting of the American Association for Cancer Research. March 28 - April 1, 1998, New Orleans, LA. Bcl-2 Hyperphosphorylation Occurs in G2/M Phase of the Cell Cycle. Young, K.K., Johnson, K.R., Schandl, C.A., Li, S., Fan, W., and Willingham, M.C.

3. Thirty-Second Annual MUSC Student Research Day. November 7, 1997, Charleston, SC.
a) Phosphorylation of Bcl-2 Coincides with G2/M Phase of the Cell Cycle. Young, K.K., Johnson, K.R., Li, S., Schandl, C.A., Willingham, M.C., and Fan, W.
b) 5-Fluorouracil Antagonizes Paclitaxel Cytotoxicity Against Human Solid Tumor Cells in vitro. Johnson, K.R., Miller, M.C., Young, K.K., and Fan, W.

4. Thiry-First Annual MUSC Student Research Day. November 1, 1996, Charleston, SC. The Isoelectric Point of Bcl-2. Young, K.K., Schandl, C.A., and Willingham, M.C.

SPECIALIZED TRAINING

Present - Citadel Academy of the Scholarship of Teaching, Learning, and Evaluation - Communication Across the Curriculum

Spring 2003 - attended "Critical Thinking" workshop by Dr. Laura Kaplan

Fall 2002 - attended "AD/HD: Nature and Management" workshop by Dr. Russell Barkley

Spring 2001 - completed Teaching Techniques course at Medical University of South Carolina

Spring 2000 - attended "Communication Across the Curriculum" workshop

RESEARCH SKILLS

Isoelectric focusing Mammalian cell culture
in vitro cell synchrony Immunoblot analysis
Two-Dimensional gel electrophoresis Nick translation assays
Site-directed mutagenesis Immunohistochemistry
Protein immunoprecipitation Transfection of genes into mammalian cells
PCR Bacterial co-culture

COMMUNITY SERVICE

Lowcountry Science Fair mentor
MUSC Children's Hospital volunteer
Ronald McDonald House volunteer
Communities in Schools volunteer
Red Cross blood donor

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